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The latest research articles and clinical trials for 100+ rare diseases — free, searchable, and explained in plain language for patients and families worldwide.

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Giant Cell Tumour of Bone

GCTB · ICD M9250

Also known as: Giant Cell Tumor of Bone, Osteoclastoma

Giant Cell Tumour of Bone is a rare bone tumour that most often affects young adults. It is usually non-cancerous but ca...

422 articles11 trials🇦🇺 2 AU

Latest: Successful Denosumab Treatment of a Pediatric Spinal Aneurysmal Bone C...

Systemic Lupus Erythematosus

SLE · ICD M32

Also known as: Lupus, SLE, Systemic Lupus

Systemic lupus erythematosus (lupus) is a chronic autoimmune disease in which the immune system attacks the body's own t...

2,032 articles923 trials🇦🇺 58 AU

Latest: Mechanism-endpoint matching in lupus: WILLOW Cohort B.

Multiple Sclerosis

MS · ICD G35

Also known as: MS, Disseminated Sclerosis

Multiple Sclerosis is a chronic autoimmune disease of the central nervous system in which the immune system attacks the ...

1,783 articles2016 trials🇦🇺 77 AU

Latest: Association Between Genetic Ancestry and Multiple Sclerosis Severity.

Myasthenia Gravis

MG · ICD G70.0

Also known as: MG, Myasthenia

Myasthenia gravis is a chronic autoimmune condition in which the immune system attacks the connection between nerves and...

1,508 articles196 trials🇦🇺 12 AU

Latest: A Simple Mg(SO3CF3)2-Based Electrolyte with Additive of 2-Methoxyethyl...

Cystic Fibrosis

CF · ICD E84

Also known as: Mucoviscidosis, CF

Cystic fibrosis is a genetic condition that causes thick, sticky mucus to build up in the lungs and digestive system. It...

1,494 articles947 trials🇦🇺 102 AU

Latest: Brensocatib in non-cystic fibrosis bronchiectasis: neutrophil serine p...

Sickle Cell Disease

SCD · ICD D57

Also known as: Sickle Cell Anaemia, HbSS disease

Sickle Cell Disease is an inherited blood disorder in which red blood cells become rigid and sickle-shaped, blocking blo...

1,354 articles639 trials🇦🇺 2 AU

Latest: The CYB5R3 T117S missense variant is associated with attenuated riocig...

Spinal Muscular Atrophy

SMA · ICD G12.0

Also known as: Werdnig-Hoffmann Disease, Kugelberg-Welander Disease, SMA

Spinal muscular atrophy is a genetic condition that causes muscle weakness and wasting. It affects a protein needed for ...

1,327 articles161 trials🇦🇺 10 AU

Latest: Treating Smn2B/− spinal muscular atrophy (SMA) mice with commercially ...

Idiopathic Pulmonary Fibrosis

IPF · ICD J84.1

Also known as: IPF, Pulmonary Fibrosis, Cryptogenic Fibrosing Alveolitis

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease in which scar tissue builds up in the lungs, making br...

1,315 articles514 trials🇦🇺 64 AU

Latest: Repeated instillations of bleomycin in male mice induce a perivascular...

Motor Neuron Disease

MND · ICD G12.2

Also known as: ALS, Amyotrophic Lateral Sclerosis, Lou Gehrig's Disease

Motor neuron disease (MND), also known as ALS, is a progressive neurodegenerative condition that destroys the nerve cell...

1,285 articles581 trials🇦🇺 29 AU

Latest: Natural history of 441 cases of bulbar onset motor neuron disease (MND...

Pulmonary Arterial Hypertension

PAH · ICD I27.0

Also known as: PAH, Primary Pulmonary Hypertension

Pulmonary arterial hypertension is a rare, progressive condition causing high blood pressure in the arteries supplying t...

1,252 articles756 trials🇦🇺 70 AU

Latest: Legacy contaminants and low occurrence of PAHs in Sotalia guianensis f...

Huntington's Disease

HD · ICD G10

Also known as: Huntington's Chorea, Huntington Disease, HD

Huntington's disease is a genetic condition that causes the gradual breakdown of nerve cells in the brain. It affects mo...

1,147 articles172 trials🇦🇺 17 AU

Latest: Emergent Information-Theoretic Neurology: Mapping Autism Spectrum Cond...

Scleroderma

SSc · ICD M34.9

Also known as: Systemic Sclerosis, Systemic Scleroderma, Limited Cutaneous Systemic Sclerosis

Scleroderma (systemic sclerosis) is a rare autoimmune connective tissue disease characterised by fibrosis of the skin an...

1,123 articles438 trials🇦🇺 20 AU

Latest: Enhancing the performance of solid-state supercapacitors using Li

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